About Us

Neurosurgery began in Greenville, South Carolina in 1955 when Frank Wrenn MD and Frank Espey MD started a neurosurgical practice at the Greenville General Hospital. Dr. Wrenn was a nationally respected neurosurgeon and was one of the few private practioners who became president of the American Association of Neurological Surgeons. Over the years, other physicians joined the practice and the community to practice neurosurgery in Greenville. Dr. Wrenn’s group became known as Greenville Neurosurgical Group and Dr. Espey founded the Neurosurgical Clinic. Both groups grew and flourished and merged in 1997 to form Southeastern Neurosurgical and Spine Institute. Southeastern Neurosurgical became officially affiliated with the Greenville Hospital System in 2006.

In 2009, Upstate Medical Rehabilitation, Steadman Hawkins Clinic of the Carolinas/University Medical Group Department of Orthopaedics and Proaxis Physical Therapy joined with Southeastern Neurosurgical and Spine Institute to form the first multidisciplinary neurosurgical and spine center in the Upstate of South Carolina. Committed to the total care of patients with disorders of the spine and brain, the center provides an integrated treatment approach that incorporates the expertise of both surgical and non-surgical health care providers. In conjunction with the healthcare network of the Greenville Hospital University Medical Center, Southeastern Neurosurgical and Spine Center continues to provide comprehensive patient care while advancing the understanding of brain and spinal disorders through research and education.